Inside the museum are galleries that feature exhibits ranging from regional history to art and culture worldwide. The museum staff produce exhibits that display objects from the Littleton Museum's collection of over 60,000 objects, as well as artifacts from other museums and cultural institutions. Exhibits are also loaned from reputable museums and exhibition companies, such as the Smithsonian Institution and the Mid-America Arts Alliance. Contemporary art exhibits at the museum present the work of established local artists and groups working in all media, addressing a variety of thought-provoking subject matters. There is truly something for everyone in the museum’s indoor and outdoor offerings.